Metabolic diseases encompass various conditions hindering the body's food-to-energy conversion. They disrupt metabolism, a vital process sustaining life, growth, and repair. Our body's intricate system breaks down nutrients for energy and repair. Dysregulation leads to metabolic diseases, underscoring the importance of maintaining a balanced metabolic function.
Globally, diabetes, especially Type 2 diabetes mellitus (T2DM), stands as a prevalent metabolic disorder marked by either insulin resistance or insufficient insul
in production.
Metabolic disorders such as obesity, Gaucher's disease, phenylketonuria (PKU), medium-chain acyl-CoA dehydrogenase deficiency (MCADD), maple syrup urine disease (MSUD), and hemochromatosis exhibit symptoms like fatigue, weight fluctuations, and nausea.
In India, these conditions pose a significant health threat due to their increasing prevalence, burdening public health systems. Studies indicate that in urban Indian populations, approximately 25% show age-adjusted prevalence of metabolic syndrome—a combination of abdominal obesity, high blood pressure, impaired fasting glucose, elevated triglyceride levels, and low HDL cholesterol. This syndrome escalates the risk of heart disease, stroke, and diabetes.
Dr. Vikramjeet Singh, Senior Consultant in Internal Medicine at Aakash Healthcare, New Delhi, highlighted to India Today. "The etiology of metabolic diseases isn't always clear-cut and can arise from various factors. Lifestyle choices, including diet and physical activity, significantly influence their development. Genetic predisposition also plays a pivotal role in how our bodies metabolize energy. Moreover, organ dysfunction contributes to these conditions."
How to prevent metabolic diseases?
To combat metabolic disease threats, India must prioritize interventions promoting physical activity, healthy diets, and regular check-ups. Dr. Vikramjeet advises maintaining weight, abstaining from alcohol and smoking, and considering medications for insulin or thyroid issues. Restorative sleep is crucial for nutrient absorption regulation.
Sources -India Today
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